Breeding Physiology

Placement of Prolactin on Pig Chromosome 7 by Linkage and Physical Mapping

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Abstract

The study of genes which code for functional protein products have important implications in comparative genetic mapping and perhaps to the swine industry. The identification of a polymorphism, or change at the DNA level, is used to assign these genes to their corresponding chromosomes by the statistical method of two-point linkage analysis. A polymorphism was detected in the Prolactin gene (PRL) and was used to linkage map PRL to pig chromosome 7. To confirm this location, PRL also was genetically physically mapped using a pig x rodent somatic cell hybrid panel. These results confirm that the short arm of pig 7 contains another of the genes on human chromosome 6.

Keywords: ASL R1379

How to Cite:

Vincent, A. L., Wang, L. & Rothschild, M. F., (1997) “Placement of Prolactin on Pig Chromosome 7 by Linkage and Physical Mapping”, Iowa State University Animal Industry Report 1(1).